{"id":103772,"date":"2022-03-23T05:15:07","date_gmt":"2022-03-23T05:15:07","guid":{"rendered":"https:\/\/www.memphasys.com\/?page_id=103772"},"modified":"2023-09-20T12:35:27","modified_gmt":"2023-09-20T02:35:27","slug":"product","status":"publish","type":"page","link":"https:\/\/www.memphasys.com\/product\/","title":{"rendered":"Product"},"content":{"rendered":"<div data-parent=\"true\" class=\"vc_row inverted-device-order style-color-lxmt-bg row-container\" id=\"row-unique-0\" data-bg-changer=\"row-unique-0\" data-bg-remove=\"style-color-lxmt-bg\" data-bg-color=\"style-color-lxmt-bg\"><div class=\"row col-double-gutter quad-top-padding single-bottom-padding single-h-padding limit-width row-parent\"><div class=\"wpb_row row-inner\"><div class=\"wpb_column pos-middle pos-center align_left column_parent col-lg-12 single-internal-gutter\"><div class=\"uncol style-light\"  data-skin-change=\"style-light\"><div class=\"uncoltable\"><div class=\"uncell no-block-padding\" ><div class=\"uncont\"><div class=\"vc_custom_heading_wrap \"><div class=\"heading-text el-text bottom-t-top animate_when_almost_visible\" ><h2 class=\"font-weight-300\" ><span>Memphasys is a reproductive biotechnology company driven by market needs to provide reproduction and fertility solutions for humans and animals alike. Products in the development pipeline include a range of devices, media, and <em>in vitro<\/em> diagnostic solutions.<\/span><\/h2><\/div><div class=\"clear\"><\/div><\/div><div class=\"vc_custom_heading_wrap \"><div class=\"heading-text el-text bottom-t-top animate_when_almost_visible\" ><h2 class=\"font-weight-300\" ><span>The driving force for Memphasys is the belief and desire to research, develop and commercialise assisted reproductive systems and methods in humans and animals.<\/span><\/h2><\/div><div class=\"clear\"><\/div><\/div><div class=\"vc_custom_heading_wrap \"><div class=\"heading-text el-text bottom-t-top animate_when_almost_visible\" ><h4 class=\"font-130700 fontsize-103814 fontspace-781688 font-weight-200\" ><span>better technology, more life&#8230;<\/span><\/h4><\/div><div class=\"clear\"><\/div><\/div><div id=\"gallery-505529\" class=\"isotope-system isotope-general-light grid-general-light\">\n\t\t\t\t\n\t<div class=\"isotope-wrapper grid-wrapper no-gutter\">\n\t\t\t\t\t\t<div class=\"isotope-container isotope-layout style-metro\" data-type=\"metro\" data-layout=\"masonry\" data-lg=\"1000\" data-md=\"600\" data-sm=\"480\">\n<div class=\"tmb tmb-iso-w9 tmb-iso-h6 tmb-light tmb-text-showed tmb-overlay-text-anim tmb-overlay-showed tmb-overlay-anim tmb-overlay-bottom tmb-overlay-text-center tmb-image-anim tmb-entry-title-uppercase tmb-id-103351  tmb-media-first tmb-media-last tmb-content-overlay tmb-no-bg\" ><div class=\"t-inside animate_when_almost_visible bottom-t-top\" ><div class=\"t-entry-visual\"><div class=\"t-entry-visual-tc\"><div class=\"t-entry-visual-cont\"><a tabindex=\"-1\" href=\"https:\/\/www.memphasys.com\/about-us\/what-we-do-humans\/\" data-lb-index=\"0\"><div class=\"t-entry-visual-overlay\"><div class=\"t-entry-visual-overlay-in style-dark-bg\" style=\"opacity: 0.15;\"><\/div><\/div><div class=\"t-overlay-wrap\"><div class=\"t-overlay-inner\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"t-overlay-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"t-overlay-text single-block-padding\"><div class=\"t-entry\"><h3 class=\"t-entry-title h4 fontspace-210350 title-scale\">WHAT WE DO - HUMANS<\/h3><div class=\"spacer spacer-one half-space\"><\/div><i class=\"fa fa-plus2 t-overlay-icon\"><\/i><\/div><\/div><\/div><\/div><\/div><div class=\"t-background-cover\" style=\"background-image:url('https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-Lock-Stock-Babies-Artificial-Insemintaion-uai-1620x1080.jpg')\"><\/div><\/a><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div><\/div><\/div><div class=\"tmb tmb-iso-w3 tmb-iso-h3 tmb-light tmb-text-showed tmb-overlay-text-anim tmb-overlay-showed tmb-overlay-anim tmb-overlay-bottom tmb-overlay-text-center tmb-image-anim tmb-entry-title-uppercase tmb-id-103263  tmb-media-first tmb-media-last tmb-content-overlay tmb-no-bg\" ><div class=\"t-inside animate_when_almost_visible bottom-t-top\" ><div class=\"t-entry-visual\"><div class=\"t-entry-visual-tc\"><div class=\"t-entry-visual-cont\"><a tabindex=\"-1\" href=\"https:\/\/www.memphasys.com\/about-us\/what-we-do-animals\/\" data-lb-index=\"1\"><div class=\"t-entry-visual-overlay\"><div class=\"t-entry-visual-overlay-in style-dark-bg\" style=\"opacity: 0.15;\"><\/div><\/div><div class=\"t-overlay-wrap\"><div class=\"t-overlay-inner\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"t-overlay-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"t-overlay-text single-block-padding\"><div class=\"t-entry\"><h3 class=\"t-entry-title h4 fontspace-210350 title-scale\">WHAT WE DO - ANIMALS<\/h3><div class=\"spacer spacer-one half-space\"><\/div><i class=\"fa fa-plus2 t-overlay-icon\"><\/i><\/div><\/div><\/div><\/div><\/div><div class=\"t-background-cover\" style=\"background-image:url('https:\/\/www.memphasys.com\/wp-content\/uploads\/2021\/12\/Memphasys-Cow-uai-563x563.jpg')\"><\/div><\/a><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div><\/div><\/div><div class=\"tmb tmb-iso-w3 tmb-iso-h3 tmb-light tmb-text-showed tmb-overlay-text-anim tmb-overlay-showed tmb-overlay-anim tmb-overlay-top tmb-overlay-text-center tmb-image-anim tmb-entry-title-uppercase tmb-id-103264  tmb-media-first tmb-media-last tmb-content-overlay tmb-no-bg\" ><div class=\"t-inside animate_when_almost_visible bottom-t-top\" ><div class=\"t-entry-visual\"><div class=\"t-entry-visual-tc\"><div class=\"t-entry-visual-cont\"><a tabindex=\"-1\" href=\"https:\/\/www.memphasys.com\/about-us\/what-we-do-animals\/\" data-lb-index=\"2\"><div class=\"t-entry-visual-overlay\"><div class=\"t-entry-visual-overlay-in style-dark-bg\" style=\"opacity: 0.15;\"><\/div><\/div><div class=\"t-overlay-wrap\"><div class=\"t-overlay-inner\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"t-overlay-content\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"t-overlay-text single-block-padding\"><div class=\"t-entry\"><h3 class=\"t-entry-title h4 fontspace-210350 title-scale\">WHAT WE DO - ANIMALS<\/h3><div class=\"spacer spacer-one half-space\"><\/div><i class=\"fa fa-plus2 t-overlay-icon\"><\/i><\/div><\/div><\/div><\/div><\/div><div class=\"t-background-cover\" style=\"background-image:url('https:\/\/www.memphasys.com\/wp-content\/uploads\/2021\/12\/Memphasys-Horses-uai-563x563.jpg')\"><\/div><\/a><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div><\/div><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\t\n<\/div>\n\n<div class=\"empty-space empty-single\" ><span class=\"empty-space-inner\"><\/span><\/div>\n<div class=\"vc_custom_heading_wrap \"><div class=\"heading-text el-text bottom-t-top animate_when_almost_visible\" ><h2 class=\"\" ><span>Product Pipeline &#8211; Summary<\/span><\/h2><\/div><div class=\"clear\"><\/div><\/div><div class=\"uncode-single-media  text-left animate_when_almost_visible bottom-t-top\"><div class=\"single-wrapper\" style=\"max-width: 100%;\"><div class=\"tmb tmb-light  tmb-media-first tmb-media-last tmb-content-overlay tmb-no-bg\"><div class=\"t-inside\"><div class=\"t-entry-visual\"><div class=\"t-entry-visual-tc\"><div class=\"uncode-single-media-wrapper\"><img decoding=\"async\" class=\"wp-image-104972\" src=\"https:\/\/www.memphasys.com\/wp-content\/uploads\/2023\/09\/1.png\" width=\"1037\" height=\"512\" alt=\"\" srcset=\"https:\/\/www.memphasys.com\/wp-content\/uploads\/2023\/09\/1.png 1037w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2023\/09\/1-300x148.png 300w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2023\/09\/1-1024x506.png 1024w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2023\/09\/1-768x379.png 768w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2023\/09\/1-18x9.png 18w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2023\/09\/1-350x173.png 350w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2023\/09\/1-uai-720x355.png 720w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2023\/09\/1-uai-1032x510.png 1032w\" sizes=\"(max-width: 1037px) 100vw, 1037px\" \/><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div><\/div><\/div><\/div><\/div><div class=\"uncode_text_column\" ><p><b>Other products in development include:<\/b><\/p>\n<ul>\n<li>A long-term ambient temperature storage medium for human sperm.<\/li>\n<li>A medium for human sperm isolation, fertilisation and cryopreservation.<\/li>\n<li>A concept for the isolation of a small number of extremely high-quality sperm for human intracytoplasmic spermatozoa injection (ICSI) assisted reproductive technology (ART).<\/li>\n<\/ul>\n<p>\n<\/div><\/div><\/div><\/div><\/div><\/div><script id=\"script-row-unique-0\" data-row=\"script-row-unique-0\" type=\"text\/javascript\" class=\"vc_controls\">UNCODE.initRow(document.getElementById(\"row-unique-0\"));<\/script><\/div><\/div><\/div><div data-parent=\"true\" class=\"vc_row row-container\" id=\"row-unique-1\"><div class=\"row double-top-padding quad-bottom-padding single-h-padding limit-width row-parent\"><div class=\"wpb_row row-inner\"><div class=\"wpb_column pos-top pos-center align_left column_parent col-lg-12 single-internal-gutter\"><div class=\"uncol style-dark\"  ><div class=\"uncoltable\"><div class=\"uncell no-block-padding\" ><div class=\"uncont\"><div class=\"vc_row row-internal row-container\"><div class=\"row row-child\"><div class=\"wpb_row row-inner\"><div class=\"wpb_column pos-top pos-center align_left column_child col-lg-6 single-internal-gutter\"><div class=\"uncol style-light\" ><div class=\"uncoltable\"><div class=\"uncell no-block-padding\" ><div class=\"uncont\"><div class=\"vc_custom_heading_wrap \"><div class=\"heading-text el-text bottom-t-top animate_when_almost_visible\" ><\/p>\n<div dir=\"ltr\">\n<div class=\"\">\n<h2><span class=\"\">Product background<\/span><\/h2>\n<\/div>\n<\/div>\n<p>\n<\/div><div class=\"clear\"><\/div><\/div><div class=\"uncode_text_column bottom-t-top animate_when_almost_visible\" data-delay=\"100\"><p>Memphasys originated as a company producing electrophoresis products and specialist polymer membranes for electrophoretic cell separation.<\/p>\n<p>Using the Company\u2019s original laboratory electrophoretic cell separation system, Professor John Aitken commenced his original investigation into separation of sperm from semen. Professor Aitken was looking for another method to improve the traditional laboratory methods for separating sperm, a process that is required for every IVF procedure.<\/p>\n<p>Currently, the most common global method for separating sperm from semen in IVF clinics is the density gradient centrifugation (DGC) system.\u00a0 In the DGC method, the density gradient selects morphologically normal sperm cells based on their specific density<sup>1-3<\/sup>. However, exposing sperm to several centrifugation steps during this procedure may damage sperm DNA. So dense sperm can still have poor DNA, even if they are progressively motile<sup>3-6<\/sup>. Moreover, the DGC method for sperm separation is labour intensive and can take up to 30\u201345 minutes to perform<sup>1-3<\/sup>.<\/p>\n<p>In 2007, a pregnancy was achieved using a perm isolation technique that selected sperm on the basis of their size and charge rather than the traditional criteria of sperm density or motility<sup>7<\/sup>.\u00a0 The CS10 device used in this formative clinical study was the technology that led to the development of the current Felix\u2122 device.<\/p>\n<p>The CS-10 method of electrophoretic sperm isolation was subsequently patented but multiple attempts to generate a commercial product were unsuccessful until Memphasys took over the development of this system in 2015. With their engineering partners, Hydrix, Memphasys has turned this general concept into a functional, practical instrument, the Felix\u2122 device, that was successful in winning two Good Design Awards in 2020.<\/p>\n<p>The Felix\u2122 device separates sperm from raw semen by a proprietary process combining electrophoresis and size exclusion membranes that allow sperm into the harvest chamber while excluding cellular contaminants such as leukocytes and precursor germ cells.<\/p>\n<\/div><div class=\"uncode_text_column text-small bottom-t-top animate_when_almost_visible\" data-delay=\"100\"><p>1. Muratori M, Tarozzi N, Cambi M, Boni L, Iorio AL, Passaro C, et al. Variation of DNA Fragmentation Levels During Density Gradient Sperm Selection for Assisted Reproduction Techniques: A Possible New Male Predictive Parameter of Pregnancy? Medicine (Baltimore). 2016;95(20):e3624.<\/p>\n<p>2. Pinto S, Carrageta DF, Alves MG, Rocha A, Agarwal A, Barros A, et al. Sperm selection strategies and their impact on assisted reproductive technology outcomes. Andrologia. 2021;53(2):e13725.<\/p>\n<p>3. Raad G, Bakos HW, Bazzi M, Mourad Y, Fakih F, Shayya S, et al. Differential impact of four sperm preparation techniques on sperm motility, morphology, DNA fragmentation, acrosome status, oxidative stress, and mitochondrial activity: A prospective study. Andrology. 2021;9(5):1549-59.<\/p>\n<p>4. Morrell JM, Rodriguez-Martinez H. Practical applications of sperm selection techniques as a tool for improving reproductive efficiency. Vet Med Int. 2010;2011.<\/p>\n<p>5. Ghaleno LR, Valojerdi MR, Janzamin E, Chehrazi M, Sharbatoghli M, Yazdi RS. Evaluation of conventional semen parameters, intracellular reactive oxygen species, DNA fragmentation and dysfunction of mitochondrial membrane potential after semen preparation techniques: a flow cytometric study. Arch Gynecol Obstet. 2014;289(1):173-80.<\/p>\n<p>6. Matson PL, Myssonski K, Yovich S, Morrison L, Irving J, Bakos HW. The density of human semen and the validation of weight as an indicator of volume: a multicentre study. Reprod Biol. 2010;10(2):141-53.<\/p>\n<p>7. Ainsworth C, Nixon B, Jansen RP, Aitken RJ. First recorded pregnancy and normal birth after ICSI using electrophoretically isolated sperm. Hum Reprod. 2007;22(1):197-200.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><div class=\"wpb_column pos-top pos-center align_center column_child col-lg-6 no-internal-gutter\"><div class=\"uncol style-light sticky-element sticky-sidebar\" ><div class=\"uncoltable\"><div class=\"uncell no-block-padding\" ><div class=\"uncont\"><div class=\"uncode-single-media  text-left animate_when_almost_visible bottom-t-top\"><div class=\"single-wrapper\" style=\"max-width: 100%;\"><div class=\"tmb tmb-light  tmb-media-first tmb-media-last tmb-content-overlay tmb-no-bg\"><div class=\"t-inside\"><div class=\"t-entry-visual\"><div class=\"t-entry-visual-tc\"><div class=\"uncode-single-media-wrapper\"><img decoding=\"async\" class=\"wp-image-103393\" src=\"https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-How-it-Works-Felix-System-Lock-Stock.jpg\" width=\"1277\" height=\"1920\" alt=\"\" srcset=\"https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-How-it-Works-Felix-System-Lock-Stock.jpg 1277w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-How-it-Works-Felix-System-Lock-Stock-200x300.jpg 200w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-How-it-Works-Felix-System-Lock-Stock-681x1024.jpg 681w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-How-it-Works-Felix-System-Lock-Stock-768x1155.jpg 768w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-How-it-Works-Felix-System-Lock-Stock-1022x1536.jpg 1022w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-How-it-Works-Felix-System-Lock-Stock-600x902.jpg 600w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-How-it-Works-Felix-System-Lock-Stock-uai-720x1083.jpg 720w, https:\/\/www.memphasys.com\/wp-content\/uploads\/2022\/01\/Memphasys-How-it-Works-Felix-System-Lock-Stock-uai-1032x1552.jpg 1032w\" sizes=\"(max-width: 1277px) 100vw, 1277px\" \/><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><script id=\"script-row-unique-1\" data-row=\"script-row-unique-1\" type=\"text\/javascript\" class=\"vc_controls\">UNCODE.initRow(document.getElementById(\"row-unique-1\"));<\/script><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"Memphasys is a reproductive biotechnology company driven by market needs to provide reproduction and fertility solutions for humans and animals [...]","protected":false},"author":2,"featured_media":103278,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"content-type":"","footnotes":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.5 - 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